Metabolite proton T 2 mapping in the healthy rhesus macaque brain at 3 T

Brain metabolites B1-corrected proton T1 mapping in the rhesus macaque at 3 T.

The accuracy of metabolic quantification in MR spectroscopy is limited by the unknown radiofrequency field and T(1). To address both issues in proton ((1)H) MR spectroscopy, we obtained radiofrequency field-corrected T(1) maps of N-acetylaspartate, choline, and creatine in five healthy rhesus macaques at 3 T. For efficient use of the 4 hour experiment, we used a new three-point protocol that op...

Proton T (1) and T (2) relaxation times of human brain metabolites at 3 Tesla.

Longitudinal and transverse relaxation times were measured for proton MRS signals from human brain metabolites at 3 T using a short-echo STEAM protocol and a surface coil as a transmitter/receiver. Volumes of interest containing mostly grey or mostly white matter were selected in occipital lobes of healthy subjects and relaxation times for the following resonances were obtained: N-acetylasparta...

Memory in Rhesus Macaque Development and Homeostasis of T Cell

Ultra-high resolution brain metabolite mapping at 7 T by short-TR Hadamard-encoded FID-MRSI

MRSI in the brain at ≥7 T is a technique of great promise, but has been limited mainly by low B0/B1+-homogeneity, specific absorption rate restrictions, long measurement times, and low spatial resolution. To overcome these limitations, we propose an ultra-high resolution (UHR) MRSI sequence that provides a 128×128 matrix with a nominal voxel volume of 1.7×1.7×8mm3 in a comparatively short measu...

Myocardial T1 mapping at 3 T in healthy adults: reference values and influencing factors

Methods Forty six healthy volunteers (26 females; mean age 49 ± 14 years) underwent left-ventricular T1 mapping in 3 short-axis slices at 3 T. For T1 mapping, modified Look-Locker inversion recovery sequence was used before and after injection of gadolinium contrast. T1 relaxation times were quantified for each slice and extracellular volume fraction (ECV) was calculated. The association betwee...